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World Hemophilia Day: Blood Clotting Factors and How To Cure Them

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Every year, April 17 is observed as World Hemophilia Day. Hemophilia is a bleeding disorder in which the blood doesn’t clot in the usual way. While Hemophilia A is caused by deficiency of clotting Factor VIII, Hemophilia B is caused by deficiency of Factor IX. Hemophilia A and B are both inherited in X-linked recessive pattern of genetics. Thus, males are most commonly affected by Hemophilia A and B, and females are usually carriers of the disease. The severity of the disease, however, varies from individual to individual.

Hemophilia makes a person bleed from any site in the body. The condition can damage joints because of repeated episodes of bleeding.

A person with hemophilia lacks enough blood-clotting proteins or clotting factors. Small cuts don’t cause much of a hassle among people with haemophilia. However, it is the deep bleeding inside the body which is a major cause of concern. This is especially if the bleeding happens in ankles, knees and elbows. Internal bleeding because of haemophilia can be life-threatening as it can cause damage to organs and tissues.

 

Hemophilia symptoms

Depending on the clotting factors, signs and symptoms of haemophilia vary from person to person. Among people whose clotting factor is only mildly reduced, the bleeding might occur only after a surgery or trauma. But in case of severe deficiency of clotting factor, the bleeding is severe and spontaneous.

Spontaneous bleeding is characterised by excessive bleeding from cuts and injuries, or excessive bleeding after a surgery or a dental operation. If a person has numerous large and deep bruises, it might be because of spontaneous bleeding. People with spontaneous bleeding also experience unusual bleeding after vaccinations, pain and swelling in joints, blood in urine and/or stool, sudden nose bleeding and unexplained irritability in infants.

Causes for hemophilia

While most forms of hemophilia are inherited, about 30% of them happen to people without any family history of the disorder. These people suffer from the condition because of an unexpected change or spontaneous mutation in the genes.

A rare form of hemophilia is known as acquired hemophilia, in which a person clotting factors in the blood are attacked by a person’s immune system. This condition can be associated with multiple sclerosis, autoimmune conditions and pregnancy.

Bleeding in the brain

People with severe hemphilia might experience bleeding in the brain with a slight bump in the head. Symptoms for bleeding in the brain include severe and prolonged headaches, repeated vomiting, lethargy, weakness and convulsions.

Inheritance of hemophilia

Hemophilia is known to be passed from mothers to son through one of mother’s genes. Most women are simply carriers and experience no symptoms of hemophilia. However, some carriers can experience symptoms of bleeding in case their clotting factors are reduced mildly.

When to seek treatment

In case you witness symptoms of bleeding in the brain, an injury in which the bleeding won’t stop or swollen joints that are extremely hot and painful, you need to seek treatment for hemophilia.

Treatment of hemophilia

Replacement of the specific clotting factor is the main treatment of hemophilia. This replacement therapy helps in stopping the bleeding episode which is in progress. The clotting factor can be replaced through donated blood or recombinant clotting factors which aren’t made from human blood.

  1. Physical therapy

A physical therapy can help in easing symptoms if there has been damage to joints because of internal bleeding. Severe damage to joints may need treatment through surgery.

  1. Clot-preserving medications

These medicines help in preventing breakdown of blood clots.

  1. Desmopressin

This treatment is used in case of milk hemophilia. Desmopressin is a hormone which can stimulate your body to release more clotting factors. The hormone is injected in the body through a vein or is provided as a nasal spray.
4. Fibrin sealants

These are medicines which are applied directly on the wounds in order to promote blood clotting and healing. This kind of treatment is helpful in dental therapy.

  1. First aid

For minor cuts, using bandages and pressure can take care of the bleeding. Ice pack can be used to treat bleeding beneath the skin. To reduce bleeding in the mouth, you can use ice pops.

  1. Vaccinations

Immunisation against hepatitis A and B can he taken in order prevent symptoms of hemophilia.


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Health

Skin Ageing Worrying You? Make These Food Swaps Now!

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Do you know what foods to eat to reverse ageing? You may be surprised to know that it is no rocket science. For a younger-looking, clear and radiant skin, all you really need is a healthy diet with lots of fresh fruits and vegetables and regular exercise. And while you may be following everything that is part of a healthy lifestyle, but still have fine lines or wrinkles on your skin. This may be because of a poor diet, chronic stress and use of beauty products with harmful chemicals.

Along with using the right kind of products for your skin, a couple of food swaps can take a long way in terms of preventing skin ageing and signs of ageing like wrinkles, fine lines, spots, dark circles etc.

Making a few nutrient-rich beauty food swaps can provide you with phytonutrients, antioxidants, vitamins and minerals that promote and support the essential functions of skin. These foods can prevent and reverse effects of ageing on the skin.

 

Food swaps to prevent ageing

  1. Processed food with low GI foods

High glcyemic index (GI) or processed foods like white bread, cake, pasta and white rice can be swapped by low GI goods like whole foods like whole wheat, brown rice and sweet potatoes.

High GI goods can cause spike in blood sugar levels, which results in more insulin entering the blood stream, thus increasing inflammation. Inflammation causes oxidative stress in the body, which threaten production of collagen and DNA, and result in fine lines and wrinkles.

  1. Refined sugar with natural sweeteners

Refined sugar can again cause spike in blood sugar, thus interfering with skin’s collagen and elastin production. Replace them with natural sweeteners like jaggery, honey, coconut sugar and dates. Natural sweetness in fruits and vegetables can be beneficial for delaying skin ageing. Fruits like berries, apples and oranges are rich in Vitamin C, fibre and antioxidants that are great for the skin. Antioxidants in these fruits neutralise free radicals that result in premature ageing of the skin.

  1. Fried food for omega 3 fatty acids

Greasy fried foods can trigger acne breakouts. What’s more is that they can contribute to weight gain, type 2 diabetes and cause free radical damage that can cause premature ageing of the skin. Replace them with omega 3 fatty acids rich foods like walnuts, fatty fish, olive oil and coconut oil. Not only are omega 3 fatty acids great for heart health, they are good for retaining the glow on your skin.

  1. Coffee with green tea

Caffeine in coffee works as a diuretic which can dehydrate your skin and make it dry. It can also cause dullness on skin that can make you look way older than you are. Opt for detoxifying green tea for a fresh and younger looking skin. Green tea contains caffeine, but in very small amounts. This will give you the energy boost you need. Polyphenols in green tea can moisturise your skin, slow down the ageing process and also fight the damage caused by free radicals.

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Health

Light physical activity may lower CVD risk in women

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While strolling or running are beneficial for heart health, light physical activity, such as gardening and folding clothes, may also lower the risk of cardiovascular diseases (CVD) in older women, say researchers.

The study showed that such activities might be enough to significantly reduce stroke or heart failure by up to 22 per cent and the risk of heart attack or coronary death by as much as 42 per cent.

The association was strong across all racial and ethnic groups, noted the study published in the journal JAMA Network Open.

 

“The higher the amount of activity, the lower the risk,” said co-author Andrea LaCroix, Researcher at the University of California, San Diego.

“And the risk reduction showed regardless of the women’s overall health status, functional ability or even age. In other words, the association with light physical activity was apparent regardless of these other factors,” LaCroix added.

For the study, researchers studied nearly 6,000 women aged 63 to 97. They were made to wear a device which measured their movement 24 hours a day for seven consecutive days.

The device was also calibrated by age to distinguish between light, and moderate-to-vigorous physical activity.

Most people do not think of folding clothes or walking to the mailbox as physical activity of any kind, the researchers said.

“This study suggests that for older women, any and all movement counts towards better cardiovascular health,” said David Goff, Director at National Heart, Lung, and Blood Institute (NHLBI) in the US.

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These Two Foods Should Definitely Be In Your Diet If You Are On A Weight Loss Program

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When it comes to weight loss, we all know that healthy eating is extremely important. However, when we talk of healthy eating, there may be some peculiarities which need to be followed. This includes keeping an eye on how much protein, fats, carbs and fibre you should be eating. Time and again, it has been said that increasing the intake of proteins and cutting down on intake of carbs and fats can help you lose weight but not health. This is primarily because protein helps you keep full for longer and reduces your appetite. There are many protein-rich foods which can be included in your like whole eggs, chicken, legumes, dairy products, healthy nuts, whole grains and fish. Apart from these common protein-rich foods there are two protein-rich foods which can help in weight loss. In the following article, we will talk about these common foods rich in proteins and extremely healthy.

Chickpeas for weight loss

Chickpeas are extremely delicious in taste. Even better they are rich in protein and fiber, both the nutrients which are essential for weight loss. Fibre keeps you fuller for longer and protein helps in controlling your hunger pangs. The fiber content in chickpeas is also good for your digestive system. Chickpeas are high in fiber, potassium, vitamin C, and vitamin B-6 content which is beneficial for maintain the heart health. The good amounts of fiber in chickpeas helps lower the cholesterol levels and thus decreases the risk of heart diseases. Also, chickpeas contain some other nutrients like folic acid, manganese, iron, copper, magnesium, and molybdenum. You can mix chickpeas with rice or whole grains to get the wholesome amount of proteins in your diet. You can also make a chickpea salad with eggs or some cubes of cottage cheese and tofu.

 

Sweet potatoes for weight loss

Sweet potatoes are extremely nutritious and offer several health benefits. But there is a possibility that you might not know that sweet potatoes can help you to lose weight. The high amount of dietary fiber, the low calorie content all work together to make sweet potatoes a great food if you are on a weight loss program. The reason why sweet potatoes help you lose weight is due to their high amount of dietary fiber. Fiber in sweet potatoes promotes fullness for a long period of time, thereby preventing overeating in the next meal. Also, fiber takes time to digest. Foods high in fiber take time to leave your stomach and enter your digestive tract. This prevents you from overeating and thereby reducing the chances of high calorie intake which further leads to weight gain. You can have sweet potatoes in your salads or simply bake them and roast them.

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