Are you using baby wipes for your infant? If yes, then stop doing so because a new study has found that baby wipes increase the risk of developing life-threatening food allergies in children.
The genetics that alters skin absorbency, use of infant cleansing wipes that leave soap on the skin, skin exposure to allergens in dust and skin exposure to food from those providing infant care are some of the factors contributing to food allergies in babies.
Researchers said that food allergy is triggered when these factors occur together.
Joan Cook-Mills, a professor at Northwestern University in the US said,”This is a recipe for developing food allergy. It’s a major advance in our understanding of how food allergy starts early in life.”
Cook-Mills said that factors leading to food allergy can be modified in the home environment.
She said,”Reduce baby’s skin exposure to the food allergens by washing your hands before handling the baby.”
She added,”Limit use of infant wipes that leave soap on the skin. Rinse soap off with water like we used to do years ago.”
Cook-Mills made the discovery by using clinical evidence about food allergy in humans, the effects of food allergen and environmental allergen exposures and neonatal mice with genetic mutations that occur in humans.
Clinical evidence shows up to 35 per cent of children with food allergies have atopic dermatitis and much of that is explained by at least three different gene mutations that reduce the skin barrier.
Cook-Mills used a neonatal mouse model with skin barrier mutations and tried exposing its skin to food allergens like peanuts. The peanuts alone had no effect.
Babies are exposed to environmental allergens in dust in a home.
“They may not be eating food allergens as a newborn, but they are getting them on their skin. Say a sibling with peanut butter on her face kisses the baby. Or a parent is preparing food with peanuts and then handles the baby,” she said.
The top skin layer is made of fats, and the soap in the wipes disrupts that barrier, Cook-Mills said.
Skin problems that occur with skin barrier mutations may not be visible until long after a food allergy has already started.
The neonatal mice with the mutations had normal-appearing skin, and the dry itchy skin of dermatitis did not develop until the mice were a few months old, the equivalent of a young adult in human years.
After the neonatal mice received three to four skin exposures of food and dust allergens for 40 minutes during a two-week period, they were given egg or peanut by mouth.
The mice had allergic reactions at the site of skin exposure, allergic reactions in the intestine, and the severe allergic food reaction of anaphylaxis that is measured by decreased body temperature.
A skin barrier dysfunction was necessary for food allergy to develop in the mice, but there is a wide continuum of severe to mild skin dysfunction with eczema or atopic dermatitis, which in its mildest form may simply appear to be dry skin.
In patients with skin-barrier defects, there are changes in the proteins in the skin that are a result of mutations in the genes.
These gene mutations in patients are primarily heterozygous, which means there is a mutation in one of the two copies of a gene.
Accordingly, in the preclinical studies, neonatal mice were also heterozygous for skin barrier mutations.
The mice were co-exposed to food allergens such as egg and peanut proteins, allergens in dust (house dust mite or Alternaria alternata mold) and sodium lauryl sulphate, a soap present in infant cleansing wipes.
Cook-Mills said, these novel animal studies provide a basis to test interventions that will more effectively block the development of food allergy in infants and children.
6 Warning Signs of Protein Deficiency
The list containing all the roles and functions of protein can be a really long one. This nutrient is necessary for building and repairing muscles and other tissues in the body such as the blood, cartilages, bones and skin. It is also important for the production of hormones or chemicals that regulate an assortment of bodily processes. Without sufficient amounts of protein in the diet or even in supplement form, it can be hard for anyone to attain optimal health.
It doesn’t come as a surprise why a lot of vegans, weight-watchers and others who are on restrictive diets to suffer from the various symptoms of protein deficiency.
By consuming foods that contain little or no protein, the body has no choice but to utilize protein that’s already in it, causing wasting of the tissues where protein is stored, such as in the muscles.
These are some of the warning signs you will observe if you are suffering from protein deficiency:
This is not caused by excess fat as you might suspect, but by the inflammation of the salivary glands. This condition usually takes place if there’s an ongoing protein-carbohydrate imbalance within you.
Edema is the reason for this, a condition wherein excessive fluid collect in the tissues. This happens because protein is one of the various components that factor in your body’s fluid balance.
Again, this has something to do with the pooling of water in the tissues, known in the medical world as edema. There’s an assortment of health conditions that lead to edema, and one of them is protein deficiency.
This condition may be brought about by a handful of things. One of them is not having enough protein in the diet. This doesn’t really come as a surprise as your hair is mostly made up of protein.
Excessive skin dryness
Not getting enough protein can cause the skin to end up really dry and flaky, and even develop rashes. Protein deficiency makes you more prone to getting sunburned too.
Lethargy or brain fog
Your energy and cognitive functioning are also affected when protein deficiency strikes. As mentioned earlier, protein is vital for the normal production of hormones. Some of these hormones have something to do with stress, energy production and mental alertness.
To avoid these problems, it’s important to get sufficient amounts of protein daily. There is a simple formula for calculating how much protein you need to consume everyday: your weight in pounds / 2 = daily protein requirement in grams.
Common protein form linked to cardiac, metabolic diseases: Study
A form of protein, clusterin, has been associated with many different facets of cardiometabolic syndrome risk through its actions in the liver, suggests a new research study.
In addition, it is linked to increased cardiovascular disease risk and mortality, high blood pressure, harmful cholesterol levels and fatty liver disease.
Cardiometabolic syndrome (CMS) is a cluster of conditions that increase a person’s risk of heart disease, stroke and diabetes. These conditions include high blood pressure, high blood sugar, excess body fat around the waist and abnormal cholesterol or triglyceride levels.
“Our goal was to discover new factors produced by the cells in fat tissue that have an impact on cardiometabolic disease.
In particular, we wanted to identify those important to maintaining the framework of fat tissue, called the extracellular matrix, which becomes dysfunctional in obesity,” said David Bradley, Assistant Professor at The Ohio State University in the US.For the study, the team included a small group of 54 obese and 18 lean patients.
The findings, published in the journal, Diabetes Care, showed that clusterin, which is overproduced from the fat cells of obese patients, is strongly related to insulin resistance, said the study.
Insulin resistance is a major cause of Type-2 Diabetes, and patients with obesity commonly have both metabolic and cardiovascular complications. “Fat cells increase clusterin production as they enlarge in obesity.
Clusterin may be a biomarker of disease, as well as a therapeutic target to potentially prevent this disease,” said lead researcher Willa Hsueh, Professor at the varsity. “This collaborative research is shedding new light on the importance of clusterin on ‘cardiometabolic syndrome’, which may eventually lead to developing new treatments for this life-threatening combination of diabetes, high blood pressure and obesity,” said K. Craig Kent, dean at the varsity.
CMS, which affects about 25 per cent of the world’s population, is now recognised as a disease entity by the World Health Organization and the American Society of Endocrinology. Further translational research involving mouse models is needed to learn more about how clusterin impacts each of the CMS components and whether administrating clusterin-inhibiting antibodies inhibits CMS, the study noted.
Drinking orange juice daily may keep strokes at bay
Drinking orange juice daily may cut your risk of deadly strokes by almost a quarter, suggests a study. The study, published in the British Journal of Nutrition, showed that people who consumed the juice each day saw a reduction in the risk of a brain clot by 24 per cent, the Daily Mail reported.
Further, the rates of heart disease were also reduced in regular drinkers, who were 12 to 13 per cent less likely to suffer with damaged arteries.Fresh fruit juices have long been thought of as healthy.
But consumers in recent years have been put off by warnings over their high sugar content.Advertise With Us The researchers noted that the health benefits in terms of stroke prevention could outweigh the risks from sugar content. “We found a favourable association with pure fruit juice consumption,” said researchers from the Netherlands National Institute for Public Health.
It’s not just orange juice that has this benefit, other fruit juices also appear to cut the risk, they noted. Juice is thought to contain many of the naturally-occurring plant substances found in whole fruit that can protect blood vessels against disease. However, the team said despite the obvious benefits of juice, they would still recommend eating whole fruit as well, as there are more studies confirming its benefits. For the study, the team examined nearly 35,000 men and women aged between 20 and 70 years.